Amitriptyline for Dogs: A Comprehensive Guide

As a pet parent, understanding the medications prescribed to your dog is crucial. One such medication, Amitriptyline, is increasingly used in the field of veterinary medicine. Originally developed to manage depression in humans, it has found use in dogs for a variety of reasons. In this guide, we will discuss the uses, dosage, side effects, and reviews of Amitriptyline for dogs.

What is Amitriptyline for Dogs?

Amitriptyline is a tricyclic antidepressant that increases the levels of serotonin and norepinephrine in the brain. For dogs, it is primarily used to treat separation anxiety, itching due to allergies, and certain types of pain.

Using Amitriptyline for Dogs with Anxiety

Separation anxiety is a common issue among dogs. It leads to destructive behaviors, excessive barking, and other issues when a dog is separated from its owner. Amitriptyline has been used successfully to manage separation anxiety in dogs due to its calming effects and its ability to regulate mood.

Amitriptyline for Dogs with Allergies and Itching

Amitriptyline can also help manage itching and discomfort associated with skin allergies in dogs. By reducing itchiness, Amitriptyline can prevent dogs from scratching and causing further damage to their skin.

Amitriptyline for Dogs with Pain

Interestingly, Amitriptyline has proven effective for certain types of pain in dogs, such as neuropathic pain. It’s essential to remember that Amitriptyline should only be used for pain management under the supervision of a veterinarian.

Amitriptyline for Dogs: Dosage

The dosage of Amitriptyline for dogs can vary based on the size of the dog, the condition being treated, and the individual dog’s tolerance. Always follow your veterinarian’s instructions regarding dosage. As a reference, a dosage chart may be provided by your vet to ensure the appropriate amount is given.

Amitriptyline for Dogs: Side Effects

Like all medications, Amitriptyline can cause side effects in dogs. Common side effects may include drowsiness, dry mouth, urinary retention, constipation, and changes in heart rate. If you notice any significant changes or concerning side effects, contact your vet immediately.

Amitriptyline for Dogs: Reviews

Reviews for Amitriptyline in dogs vary, with some pet owners reporting significant improvements in their dogs’ conditions and others noticing minimal effect or side effects. Remember, each dog’s response to medication can be different.

Amitriptyline for Dogs: Cost

The cost of Amitriptyline for dogs can vary based on factors like the dosage prescribed, the number of pills, and location. In general, it is considered an affordable medication.


Amitriptyline can be a valuable tool for managing certain conditions in dogs, including separation anxiety, skin allergies, and certain types of pain. However, it’s important to work closely with your vet to monitor your dog’s response to the medication and adjust the treatment plan as needed. Ensure to discuss the potential side effects, dosage, and any other concerns with your vet before starting the medication.


This article is intended to be a guide and does not replace professional veterinary advice. Always consult with your veterinarian for the best treatment options for your pet.

Please note, while we strive for accuracy, the world of veterinary medicine is constantly evolving, and new research may change our understanding of how medications like Amitriptyline work in pets. Always consult with a vet for the most current advice.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:


    • ANSM (Agence nationale de sécurité du médicament et des produits de santé):


    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios):


    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte):


    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist


    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website:

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website:


    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717


    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222


    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284


    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113


    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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