Can you feel happy on sertraline?

Sertraline is a medication that is commonly prescribed for the treatment of depression, anxiety disorders, OCD, PTSD, and PMDD. While sertraline may not necessarily make you feel happy in the traditional sense, it can help to improve your mood and overall well-being. Many individuals who take sertraline report feeling less anxious, less irritable, and more motivated to engage in activities they enjoy. By alleviating symptoms of depression and anxiety, sertraline can help individuals to experience a more positive outlook on life and improved overall quality of life.

It is important to note that sertraline may take several weeks to take effect. It may take time for your body to adjust to the medication and for the levels of serotonin in your brain to increase. However, with continued use, many individuals report significant improvements in their mood and overall well-being.

It is also important to manage your expectations when taking sertraline. While the medication can be an effective treatment for depression and anxiety, it may not necessarily make you feel happy in the traditional sense. It is important to work closely with your doctor to determine the best treatment plan for your unique needs and to monitor your symptoms over time.

In conclusion, while sertraline may not necessarily make you feel happy in the traditional sense, it can help to improve your mood and overall well-being with continued use. By increasing the levels of serotonin in the brain, sertraline can help to alleviate symptoms of depression and anxiety and lead to a more positive outlook on life. It is important to manage your expectations and work closely with your doctor to determine the best treatment plan for your unique needs.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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