Can You Take Chlordiazepoxide with Alcohol?

If you’re taking Chlordiazepoxide (brand name Librium) for anxiety, muscle spasms, or alcohol withdrawal, you may be wondering whether it’s safe to consume alcohol while on this medication. Understanding the risks and potential interactions between Chlordiazepoxide and alcohol is crucial for your health and safety. In this blog post, we’ll address the important question: Can you take Chlordiazepoxide with alcohol? and provide key information about the dangers of combining these substances.

What is Chlordiazepoxide?

Chlordiazepoxide is a benzodiazepine medication often prescribed to treat anxiety, muscle spasms, and alcohol withdrawal. It works by enhancing the calming effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, which helps reduce anxiety and relax muscles. Chlordiazepoxide is also used to manage alcohol withdrawal symptoms by calming the central nervous system (CNS).

Can You Take Chlordiazepoxide with Alcohol?

The short answer is no, it is not safe to take Chlordiazepoxide with alcohol. Combining these two substances can lead to dangerous side effects and increase the risk of severe health complications. Let’s explore why.

The Risks of Mixing Chlordiazepoxide and Alcohol

  1. Increased Sedation: Both Chlordiazepoxide and alcohol are CNS depressants. This means they both slow down brain activity, which can lead to excessive drowsiness, dizziness, and difficulty concentrating. When combined, the sedative effects are amplified, which can severely impair your ability to perform daily activities safely, such as driving or operating machinery.
  2. Respiratory Depression: Both Chlordiazepoxide and alcohol can depress your respiratory system, slowing your breathing. When taken together, this effect can become dangerous, potentially leading to respiratory failure, which can be life-threatening.
  3. Increased Risk of Overdose: Combining alcohol and Chlordiazepoxide significantly increases the risk of an overdose. Symptoms of overdose can include severe drowsiness, confusion, slurred speech, impaired coordination, and in extreme cases, coma or death.
  4. Impaired Judgment: Alcohol can impair judgment and decision-making. When combined with Chlordiazepoxide, which also affects cognition and concentration, you may find it harder to make sound decisions, increasing the risk of accidents and risky behavior.
  5. Liver Damage: Both alcohol and Chlordiazepoxide are metabolized by the liver. Chronic use of alcohol along with Chlordiazepoxide can place extra strain on the liver, potentially leading to liver damage or liver failure over time.

Alcohol and Chlordiazepoxide During Alcohol Withdrawal

One of the primary uses of Chlordiazepoxide is to help manage alcohol withdrawal symptoms. However, if you are in alcohol withdrawal, it is crucial that you do not drink alcohol while taking Chlordiazepoxide. While the medication helps ease withdrawal symptoms, drinking alcohol during this time can make the symptoms worse, prolong the withdrawal process, and increase the risk of severe complications, such as seizures or delirium tremens.

How Long Should You Wait After Taking Chlordiazepoxide to Drink Alcohol?

If you’ve taken Chlordiazepoxide, it’s important to wait until the medication has fully cleared your system before drinking alcohol. Given that Chlordiazepoxide has a long half-life, it can remain in your system for several days. For your safety, it’s crucial to follow your doctor’s advice regarding when it’s safe to drink alcohol after taking Chlordiazepoxide.

Conclusion

In summary, taking Chlordiazepoxide with alcohol is not safe. Combining these substances can significantly increase the risk of severe side effects, including sedation, respiratory depression, and overdose. If you are prescribed Chlordiazepoxide for anxiety, muscle spasms, or alcohol withdrawal, it’s important to avoid drinking alcohol to ensure your safety and prevent dangerous health complications. Always follow your healthcare provider’s advice regarding alcohol consumption while on this medication, and if you have any questions or concerns, be sure to consult with them directly.


For more information on Chlordiazepoxide, benzodiazepine medications, and how to safely manage alcohol withdrawal, be sure to explore our other related blog posts.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

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