Does agomelatine effect serotonin?

Yes, agomelatine does affect serotonin levels in the brain. Agomelatine is an antidepressant medication that works by modulating the activity of both melatonin and serotonin receptors in the brain. Specifically, it acts as an agonist at melatonin receptors and an antagonist at serotonin receptors.

By modulating serotonin activity in the brain, agomelatine can help regulate mood and improve symptoms of depression and anxiety. It may be particularly effective for individuals who experience disrupted sleep-wake cycles or other circadian rhythm disturbances, as serotonin plays a role in regulating sleep and wakefulness.

It is important to note that the exact mechanism of action of agomelatine is not fully understood, and its effects on neurotransmitter activity in the brain may vary from person to person. The decision to use agomelatine or any other medication should be made in consultation with a healthcare provider, who can help determine the most appropriate treatment plan based on individual needs and medical history.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: