Dopamine

« Back to Glossary Index

Dopamine is a neurotransmitter, which is a chemical messenger that transmits signals between neurons in the brain. It plays a crucial role in regulating various brain functions, such as movement, motivation, reward, learning, attention, and mood. Dopamine is produced by dopaminergic neurons in several brain regions, including the substantia nigra, the ventral tegmental area, and the hypothalamus. Dopamine acts on specific receptors in the brain, which are classified into two main types: D1-like receptors and D2-like receptors. The D1-like receptors are primarily involved in promoting activation, while the D2-like receptors are primarily involved in inhibiting activation. Dopamine dysfunction has been implicated in several neurological and psychiatric disorders, including Parkinson’s disease, schizophrenia, addiction, and depression. Medications that affect dopamine, such as haloperidol, can have significant effects on brain function and behavior.

« Back to Glossary Index