major depressive disorder

Major depressive disorder (MDD) is a mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest in activities. It affects approximately 17 million adults in the United States each year and can significantly impair daily functioning. Symptoms include sadness, appetite changes, sleep disturbances, fatigue, guilt, and suicidal thoughts. Treatment typically involves medication and therapy, such as SSRIs or SNRIs and CBT or IPT. Early treatment is important to prevent worsening symptoms and suicide risk.