How many hours does quetiapine last?

The duration of action of quetiapine can vary depending on the individual and the formulation of the medication.

Immediate-release quetiapine is typically taken two or three times per day, with a duration of action of approximately 6 to 8 hours per dose.

Extended-release quetiapine, also called quetiapine XR, is designed to release the medication slowly over a period of 24 hours, and is typically taken once daily. The duration of action of quetiapine XR can vary depending on the individual, but it generally lasts for about 24 hours.

It is important to follow all instructions for taking quetiapine and to take it on a regular schedule, as directed by a healthcare provider. Abruptly stopping quetiapine can cause withdrawal symptoms and may increase the risk of relapse. If you have any questions or concerns about the duration of action of quetiapine, it is important to discuss them with a healthcare provider.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

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