Does bupropion increase GABA?

Bupropion is not known to increase GABA (gamma-aminobutyric acid) levels in the brain. Its primary mechanism of action involves blocking the reuptake of dopamine and norepinephrine, which can improve mood, energy, and motivation levels.

GABA is another neurotransmitter in the brain that is involved in regulating mood, anxiety, and other brain functions. However, bupropion does not directly affect GABA levels or function.

While bupropion may not affect GABA levels, it may have some indirect effects on GABA function. For example, bupropion’s effects on dopamine and norepinephrine may influence GABA function and contribute to its effectiveness in treating certain conditions.

It is important to only take bupropion as prescribed by a healthcare provider and to follow their instructions carefully. If you have any questions or concerns about your medication regimen, it is important to discuss these with your healthcare provider.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: