Does risperidone improve mood?

Risperidone is an antipsychotic medication that is primarily used to treat schizophrenia and bipolar disorder. While it is not approved by the FDA for the treatment of depression, it may be used off-label in certain cases to help improve mood.

The mechanism by which risperidone may improve mood is not fully understood. However, it is believed that by blocking the action of dopamine and serotonin, two neurotransmitters that are involved in mood regulation, risperidone may help to stabilize mood and reduce symptoms of depression in some people.

There is some evidence to suggest that risperidone may be effective in treating depression in certain cases. For example, a small study published in the Journal of Clinical Psychiatry found that risperidone was effective in reducing symptoms of depression in patients who had not responded to other treatments.

However, it is important to note that risperidone can also cause side effects, some of which may be significant. These can include drowsiness, dizziness, weight gain, and movement disorders such as tardive dyskinesia. Additionally, risperidone may increase the risk of developing diabetes or other metabolic disorders.

Ultimately, whether risperidone improves mood will depend on the individual and their specific symptoms. Anyone considering taking risperidone for depression or mood stabilization should speak with their healthcare provider about the potential risks and benefits.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: