Is it OK to take mirtazapine every night?

Mirtazapine is typically prescribed to be taken once daily at bedtime, as it can cause drowsiness and has a sedative effect. It is important to follow the dosing instructions provided by your healthcare provider and not to exceed the recommended dose.

Taking mirtazapine every night as prescribed by a healthcare professional is generally considered safe for most people. However, like all medications, it can have potential side effects, and it is important to discuss any concerns or questions you have about mirtazapine with your healthcare provider.

Dosing instructions for mirtazapine

The dosing instructions for mirtazapine are as follows:

  • Mirtazapine is typically taken once daily at bedtime.
  • The starting dose is usually 15 mg per day, and the maximum recommended dose is 45 mg per day.
  • Mirtazapine can be taken with or without food.
  • It may take several weeks for the full therapeutic effects of mirtazapine to be felt.
  • It is important not to abruptly stop taking mirtazapine, as this can cause withdrawal symptoms. It is recommended to work with your healthcare provider to gradually taper off the medication if you decide to stop taking it.

It is important to note that the dosing instructions for mirtazapine can vary depending on the individual’s condition and other factors, so it is important to follow the specific instructions provided by your healthcare provider.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: