Is mirtazapine high risk?

Mirtazapine is a medication used to treat depression and other mental health conditions. It is generally considered to be safe and effective, but like all medications, it can have potential side effects and risks.

One common side effect of mirtazapine is drowsiness and sedation, which can be a concern for individuals who need to operate machinery or engage in activities that require alertness. Other side effects may include weight gain, increased appetite, and dry mouth.

While serious side effects of mirtazapine are rare, there have been cases reported of allergic reactions or a decrease in white blood cells, which can increase the risk of infection. It is important to discuss any concerns or questions about the risks and benefits of mirtazapine with a healthcare provider.

One potential risk associated with mirtazapine and other antidepressants is an increased risk of suicidal thoughts or behaviors. This risk may be higher in children, teenagers, and young adults, as well as during the first few months of treatment or during dosage changes. It is important to closely monitor individuals taking mirtazapine and to report any concerning symptoms or changes in behavior to a healthcare provider.

Despite these potential risks, mirtazapine is generally considered to be a safe medication when used as prescribed and under the supervision of a qualified healthcare provider. It is important to work closely with a healthcare provider when taking mirtazapine or any other medication to ensure that it is being used safely and effectively.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: