Paliperidone (Invega) Clinical Trials: Evaluating Safety and Effectiveness

Clinical trials are research studies conducted to evaluate the safety and effectiveness of medications, including paliperidone (the generic name for Invega). Clinical trials can help healthcare providers and researchers better understand the benefits and risks of medications and can help inform treatment decisions.

Paliperidone has been studied in numerous clinical trials for the treatment of schizophrenia and related conditions. These trials have evaluated various aspects of paliperidone, including its effectiveness, safety, and side effects.

For example, one clinical trial compared the effectiveness of paliperidone extended-release (ER) to placebo in individuals with schizophrenia. The study found that paliperidone ER was more effective than placebo in reducing symptoms of schizophrenia.

Another clinical trial evaluated the safety and tolerability of paliperidone ER in individuals with schizophrenia or schizoaffective disorder. The study found that paliperidone ER was generally well-tolerated, with common side effects including weight gain, sedation, and movement disorders.

If you are considering participating in a clinical trial for paliperidone or have concerns about the medication, it’s important to talk to your healthcare provider. They can provide guidance on the benefits and risks of participating in a clinical trial and help you make an informed decision about whether it is right for you.

In conclusion, paliperidone (Invega) has been studied in numerous clinical trials for the treatment of schizophrenia and related conditions. Clinical trials can help inform treatment decisions and provide valuable information about the benefits and risks of medications such as paliperidone. If you are considering participating in a clinical trial or have concerns about paliperidone, talk to your healthcare provider.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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