Agomelatine is a medication that is used to treat depression in adults. While it is generally well-tolerated by most individuals, there are some warnings and precautions that should be considered before starting treatment with agomelatine:
- Liver function: Agomelatine can affect liver function, and individuals with pre-existing liver disease or elevated liver enzymes should be monitored closely while taking the medication. In rare cases, agomelatine can cause severe liver injury, and individuals experiencing symptoms such as jaundice, abdominal pain, or dark urine should seek medical attention immediately.
- Suicidal thoughts and behavior: Like other antidepressant medications, agomelatine may increase the risk of suicidal thoughts and behavior, particularly in children, adolescents, and young adults. Individuals should be closely monitored for signs of suicidal ideation or behavior while taking agomelatine.
- Pregnancy: The safety of agomelatine during pregnancy is not well-established, and it should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.
- Other medications: Agomelatine may interact with other medications, particularly those that affect liver function or serotonin activity in the brain. Individuals should inform their healthcare provider of all medications, supplements, and herbal remedies they are taking before starting treatment with agomelatine.
It is important to discuss potential risks and benefits with a healthcare provider before starting treatment with agomelatine. Individuals should also follow all instructions for taking the medication and report any concerning side effects or changes in mood or behavior to their healthcare provider.