What will sertraline do to you?

Sertraline is a medication that is commonly prescribed for the treatment of depression, anxiety disorders, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). If you have been prescribed sertraline, you may be wondering what it will do to you and how it will affect your mood and overall well-being. In this article, we will explore the effects of sertraline and what you can expect when taking this medication.

Sertraline belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). These drugs work by increasing the levels of serotonin, a neurotransmitter in the brain that affects mood, in the brain. Serotonin is often referred to as the “feel-good” neurotransmitter because it is responsible for feelings of happiness and well-being.

When you take sertraline, it will increase the levels of serotonin in your brain, which can help to improve your mood and make you feel better. This can be especially helpful for people who are struggling with depression or anxiety disorders.

Sertraline can also help to reduce the symptoms of OCD, which is a disorder characterized by repetitive and intrusive thoughts or behaviors. By increasing the levels of serotonin in the brain, sertraline can help to reduce the intensity and frequency of these symptoms, allowing individuals to better manage their OCD.

PTSD is another condition that can be treated with sertraline. PTSD is a disorder that can develop after experiencing or witnessing a traumatic event, such as a serious accident, natural disaster, or military combat. Symptoms of PTSD can include flashbacks, nightmares, and feelings of numbness or detachment. Sertraline can help to reduce the severity of these symptoms, making it easier for individuals to cope with their PTSD and move forward with their lives.

PMDD is a condition that affects some women in the days leading up to their menstrual cycle. Symptoms can include mood swings, irritability, and depression. Sertraline can help to reduce the severity of these symptoms, allowing women to better manage their PMDD and improve their quality of life.

While sertraline can be very helpful for treating a variety of conditions, it is important to understand that it is not a magic pill that will instantly make all of your problems go away. It can take several weeks or even months for sertraline to start working, and it may not be effective for everyone. It is important to work closely with your doctor to find the right dose and treatment plan for you.

In addition to its therapeutic effects, sertraline can also cause side effects. Common side effects of sertraline can include nausea, diarrhea, headaches, and difficulty sleeping. These side effects are usually mild and go away on their own after a few days or weeks. However, if you experience any severe or persistent side effects, it is important to contact your doctor right away.

It is also important to note that sertraline can interact with other medications, including over-the-counter medications and supplements. It is important to let your doctor know about all of the medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements, to avoid any potential interactions.

Sertraline can also be habit-forming, and some people may experience withdrawal symptoms when they stop taking the medication. It is important to follow your doctor’s instructions when stopping sertraline to avoid any potential withdrawal symptoms.

In conclusion, sertraline is a medication that can be very helpful for treating a variety of conditions, including depression, anxiety disorders, OCD, PTSD, and PMDD. By increasing the levels of serotonin in the brain, sertraline can help to improve mood and reduce the severity of symptoms. However, it is important to understand that sertraline is not a magic pill and may not be effective for everyone. It can also cause side effects and interact with other medications. If you are considering taking sertraline, it is important to work closely with your doctor to find the right dose and treatment plan for you.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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