When is the best time to take lorazepam for sleep?

The best time to take lorazepam for sleep depends on the individual’s needs and the healthcare provider’s instructions. Lorazepam is a benzodiazepine medication that is commonly used to treat anxiety, insomnia, and other conditions that affect the central nervous system. It works by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA), which helps to reduce anxiety and promote relaxation.

For sleep, lorazepam is usually taken at bedtime, as it can cause drowsiness and sedation. However, the exact timing and dosage may vary depending on the individual’s sleep pattern, medical history, and other medications they may be taking. It’s important to follow the healthcare provider’s instructions and not to exceed the recommended dosage or duration of treatment, as lorazepam can cause side effects, such as dizziness, confusion, memory impairment, and dependence. It’s also important not to stop taking lorazepam suddenly, as this can lead to withdrawal symptoms, such as rebound insomnia, anxiety, and seizures.

If you have trouble sleeping or need to adjust your lorazepam dosage or timing, talk to your healthcare provider. They can help you determine the best course of action based on your individual needs and monitor your response to the medication. Additionally, they may suggest other treatments or lifestyle changes that can improve your sleep, such as cognitive-behavioral therapy, relaxation techniques, sleep hygiene, or exercise.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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