Can you gain weight on bupropion?

Bupropion is not typically associated with weight gain, and in some cases, it may even lead to weight loss.

In fact, bupropion is sometimes used off-label as a weight loss aid, particularly in individuals who are overweight or obese and have comorbid conditions such as depression or binge eating disorder.

However, it is important to note that weight changes can vary depending on the individual and other factors such as diet and exercise habits. Some individuals may experience weight gain or weight loss while taking bupropion, while others may not experience any significant changes in weight.

If you are concerned about weight changes while taking bupropion or any other medication, it is important to discuss this with your healthcare provider. They can help determine the underlying cause and recommend appropriate treatment options. It is also important to maintain a healthy diet and exercise regimen to promote overall health and well-being.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: