How Does Bupropion XL Make You Feel?

Bupropion XL, an extended-release formulation of the medication known as Wellbutrin, is commonly prescribed for the treatment of depression and has been found to have a positive impact on the overall well-being of many patients. As an atypical antidepressant, it distinguishes itself from other classes of depression medications through its unique effects on the brain’s chemistry, particularly by influencing the neurotransmitters dopamine and norepinephrine, rather than serotonin.

When starting bupropion XL, patients often report various changes in their feelings and mood. The medication is designed to help alleviate symptoms of depression, which can include feelings of sadness, hopelessness, and a lack of interest in activities once enjoyed. Bupropion XL works to balance the neurotransmitters in the brain, which can lead to improved mood, increased energy levels, and a reduction in depressive symptoms.

Emotional Regulation and Energy Levels

Many patients find that bupropion XL helps to stabilize their mood without causing the emotional blunting that can sometimes be associated with selective serotonin reuptake inhibitors (SSRIs). This makes bupropion a preferred option for those who want to relieve their depressive symptoms without dampening their emotional range. Patients may feel more ‘like themselves’ but without the heavy burden of depression.

Additionally, due to its stimulant-like effects, bupropion XL can lead to heightened energy levels. This can be particularly beneficial for those who struggle with the lethargy and fatigue that often accompany depression. However, it’s important to monitor these changes, as for some people, increased energy can also lead to anxiety or agitation, especially when they first start the medication.

Considerations and Side Effects

It’s crucial to discuss with a healthcare provider whether bupropion XL is the right medication for you, as it can interact with certain conditions and other medications. It’s also vital to consider the potential side effects, which can include dry mouth, weight loss or gain, and insomnia. Furthermore, there’s an increased risk of seizures with bupropion, which necessitates careful screening and dosage considerations by a healthcare professional.

Making an Informed Decision

Choosing the right antidepressant is a nuanced process that should be navigated with the guidance of a healthcare provider. For those weighing the options between Wellbutrin SR and XL, our in-depth comparison, “Is Wellbutrin SR or XL Better?”, offers valuable insights into the differences between these two formulations.

Furthermore, understanding the onset of action of bupropion is essential for setting realistic expectations for treatment. Our article, “How Quickly Does Bupropion Act?”, discusses how quickly you might begin to feel the effects of bupropion.

Lastly, since bupropion is unique among antidepressants in that it does not primarily affect serotonin, you may be curious about how it does indeed interact with this neurotransmitter. For more information on this topic, refer to our resource, “Does Bupropion Affect Serotonin?”, to expand your understanding.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: