How long can you stay on sertraline?

Sertraline is a medication that is commonly prescribed for the treatment of depression, anxiety disorders, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). If you have been prescribed sertraline, you may be wondering how long you can stay on this medication. Here is what you need to know:

Duration of treatment

The duration of sertraline treatment depends on the individual and their specific symptoms. In general, antidepressant medications like sertraline are usually taken for at least six months to a year to fully treat the symptoms of depression or anxiety. However, some individuals may need to stay on the medication for longer or shorter periods of time.

Maintenance therapy

For some individuals, staying on sertraline for a longer period of time may be necessary to prevent symptoms from returning. This is known as maintenance therapy. Maintenance therapy may be recommended for individuals with a history of recurrent depression or anxiety, or for individuals who have had a good response to sertraline in the past.

Tapering off sertraline

If you and your doctor decide that it is time to stop taking sertraline, it is important to do so gradually. Tapering off sertraline can help to minimize withdrawal symptoms, which can include dizziness, headache, and nausea. Your doctor will likely recommend gradually reducing your dosage over a period of several weeks or months.

Re-evaluation

It is important to re-evaluate the need for sertraline on a regular basis. Your doctor may recommend periodic check-ins to assess your symptoms and determine if sertraline is still necessary. If your symptoms have improved and you are no longer experiencing depression or anxiety, your doctor may recommend tapering off sertraline or discontinuing the medication altogether.

Individual factors

Ultimately, how long you stay on sertraline depends on your individual symptoms, response to the medication, and overall health and well-being. Some individuals may need to stay on sertraline for a longer period of time, while others may be able to taper off the medication sooner.

In conclusion, the duration of sertraline treatment depends on the individual and their specific symptoms. Antidepressant medications like sertraline are usually taken for at least six months to a year to fully treat the symptoms of depression or anxiety. Maintenance therapy may be recommended for some individuals to prevent symptoms from returning. Tapering off sertraline should be done gradually to minimize withdrawal symptoms, and re-evaluation is important to determine if sertraline is still necessary. By working closely with your doctor, you can determine the best treatment plan for your unique needs and stay on sertraline for the appropriate amount of time.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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