How safe is sertraline?

Sertraline is generally considered to be a safe medication when used as prescribed and under the guidance of a healthcare professional. However, like all medications, sertraline does carry some risks, and it is important to be aware of these risks before starting the medication.

Some potential side effects of sertraline include:

  1. Gastrointestinal symptoms, such as nausea, diarrhea, and constipation
  2. Headache
  3. Insomnia or drowsiness
  4. Sexual dysfunction
  5. Weight gain

Sertraline can also interact with other medications and supplements, so it is important to talk to your doctor about any other medications or supplements you are taking before starting sertraline.

In rare cases, sertraline may cause more serious side effects, such as:

  1. Suicidal thoughts or behaviors, particularly in children, adolescents, and young adults
  2. Serotonin syndrome, a potentially life-threatening condition that can occur when there is too much serotonin in the brain
  3. Seizures
  4. Hyponatremia, a condition in which there is a low level of sodium in the blood

It is important to monitor for these more serious side effects and seek medical attention immediately if they occur.

Overall, sertraline is considered to be a safe and effective medication for treating depression, anxiety, and other mood disorders. However, it is important to be aware of the potential side effects and risks associated with the medication, and to work closely with your doctor to determine the best treatment plan for your unique needs.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:


    • ANSM (Agence nationale de sécurité du médicament et des produits de santé):


    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios):


    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte):


    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist


    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website:

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website:


    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717


    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222


    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284


    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113


    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.