Is Wellbutrin (bupropion) similar to Xanax (alprazolam)?

Wellbutrin (bupropion) and Xanax (alprazolam) are not similar medications and have different mechanisms of action and clinical indications.

Wellbutrin is an antidepressant medication that primarily works by increasing the levels of dopamine and norepinephrine in the brain. It is used to treat major depressive disorder and seasonal affective disorder (SAD), as well as to aid in smoking cessation.

Xanax, on the other hand, is a benzodiazepine medication that is primarily used to treat anxiety and panic disorders. It works by enhancing the activity of gamma-aminobutyric acid (GABA) in the brain, which can produce a calming effect and reduce anxiety.

While both Wellbutrin and Xanax can affect mood and anxiety, they do so in different ways and have different clinical indications. Wellbutrin is not typically used as a first-line treatment for anxiety disorders, and Xanax is not typically used as a first-line treatment for depression.

It is important to only take these medications as prescribed by a healthcare provider and to follow their instructions carefully. If you have concerns about your medication regimen, it is important to discuss them with your healthcare provider.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: