Does bupropion affect brain?

Bupropion affects the brain by increasing the levels of certain neurotransmitters, such as dopamine and norepinephrine. These neurotransmitters are involved in regulating mood, motivation, and other brain functions.

Bupropion is classified as an atypical antidepressant or dopamine and norepinephrine reuptake inhibitor (DNRI), as it works by blocking the reuptake of dopamine and norepinephrine in the brain, which increases their availability and can improve symptoms of depression and anxiety.

Bupropion’s effects on the brain can also contribute to its effectiveness in treating other conditions, such as ADHD, smoking cessation, and seasonal affective disorder (SAD).

It is important to note that while bupropion can have positive effects on mood and other brain functions, it may also cause side effects in some individuals, such as anxiety, agitation, or insomnia. It is important to only take bupropion as prescribed by a healthcare provider and to report any side effects or concerns to them. They may be able to adjust your dose or switch you to a different medication if needed.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: