Is agomelatine a strong antidepressant?

Agomelatine is a medication that is used to treat depression and is considered to be a moderately effective antidepressant. It works by modulating the activity of the neurotransmitters melatonin and serotonin in the brain.

Studies have shown that agomelatine can be effective in reducing symptoms of depression, including low mood, loss of interest in activities, and disrupted sleep patterns. However, its effectiveness may vary from person to person, and it may not be as effective as some other antidepressant medications for certain individuals.

Agomelatine is generally well-tolerated by most individuals, with a low incidence of side effects compared to some other antidepressant medications. However, it can have side effects such as nausea, headache, and dizziness.

It is important to note that the effectiveness of agomelatine and other antidepressant medications can vary depending on the individual and the severity of their symptoms. It is recommended to discuss treatment options with a healthcare provider to determine the best course of action for managing depression.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: