Is haloperidol similar to Xanax?

No, haloperidol and Xanax are not similar medications. While they are both used to treat psychiatric disorders, they belong to different drug classes and have different mechanisms of action.

Haloperidol is an antipsychotic medication used to treat schizophrenia, acute psychosis, and Tourette’s syndrome. It works by blocking dopamine and serotonin receptors in the brain, which can help alleviate symptoms of these disorders.

On the other hand, Xanax (alprazolam) is a benzodiazepine-type anti-anxiety medication used to treat anxiety disorders and panic attacks. It enhances the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, which can help reduce feelings of anxiety.

While both medications may have similar side effects such as tiredness/fatigue, drowsiness/sedation, changes in weight, dry mouth, and constipation, they also have significant differences in their side effect profiles. For example, haloperidol may cause extrapyramidal effects (involuntary movements), gynecomastia, and menstrual irregularities, while Xanax may cause memory problems, speech problems, and headache.

There have been studies comparing the efficacy and safety of haloperidol and Xanax in treating certain conditions. For example, a study published in the Journal of Clinical Psychopharmacology found that both medications were similarly effective in treating acute agitation in patients with schizophrenia or bipolar disorder. However, haloperidol was associated with a higher incidence of extrapyramidal symptoms.

In conclusion, while haloperidol and Xanax may be used to treat psychiatric disorders, they are not similar medications and have different mechanisms of action and side effect profiles. It is important to consult with a healthcare provider to determine which medication may be most appropriate for an individual’s specific condition.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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