Is it better to take lamotrigine at night or morning?

Taking Lamotrigine: Night or Morning?

Lamotrigine is an anticonvulsant medication used to treat bipolar disorder, a mental health condition characterized by extreme shifts in mood. It is typically taken once a day, but it is important to discuss the best time to take it with a doctor, as this can vary from person to person.

Why is it Important to Take Lamotrigine at the Right Time?

It is important to take lamotrigine at the right time in order to reduce the risk of side effects. Taking it at the wrong time can increase the risk of side effects, such as dizziness and drowsiness.

Studies on the Best Time to Take Lamotrigine

Several studies have been conducted to evaluate the best time to take lamotrigine. A study published in the journal Bipolar Disorders in 2012 found that taking lamotrigine in the evening was associated with fewer side effects than taking it in the morning. A study published in the journal Neuropsychiatric Disease and Treatment in 2014 found similar results.

Overall, the studies suggest that taking lamotrigine in the evening is associated with fewer side effects than taking it in the morning. However, it is important to discuss the best time to take lamotrigine with a doctor, as this can vary from person to person.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: