Is nortriptyline a strong painkiller?

Nortriptyline is not a strong painkiller, but it may be effective in treating certain types of chronic pain, such as neuropathic pain. It is a tricyclic antidepressant that works by increasing the levels of certain neurotransmitters in the brain, including serotonin and norepinephrine, which can help to reduce pain perception.

Nortriptyline is often used off-label for the treatment of chronic pain conditions, such as neuropathic pain, migraine headaches, and fibromyalgia. It may take several weeks for nortriptyline to begin working for chronic pain, and the dosage and duration of treatment may vary depending on the individual and the condition being treated.

It is important to use nortriptyline only under the guidance of a healthcare provider, who can help determine the most appropriate treatment plan based on individual needs and medical history. Like any medication, nortriptyline can cause side effects, some of which may be serious. It may also interact with other medications, so it is important to discuss any medications or medical conditions with a healthcare provider before taking nortriptyline.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: