What is benperidol used for?

Primary Use: Treating Schizophrenia and Psychotic Disorders

Benperidol is an antipsychotic medication primarily used for treating schizophrenia and other psychotic disorders. It belongs to the butyrophenone class of drugs, which work by blocking dopamine receptors in the brain, thereby reducing psychotic symptoms such as hallucinations, delusions, and disorganized thinking.

Clinical Studies

Numerous studies have investigated the efficacy of benperidol in treating schizophrenia and psychotic disorders:

Study 1: Comparison with Haloperidol

A study by Van Praag et al. (1981) compared the efficacy of benperidol with haloperidol, another butyrophenone antipsychotic, in 60 patients with schizophrenia. The results showed that both drugs were effective in reducing psychotic symptoms, with no significant difference between the two.

Study 2: Systematic Review of Benperidol’s Effectiveness

A systematic review by Leucht et al. (2002) examined the effectiveness of benperidol in comparison to other antipsychotic medications in the treatment of schizophrenia. The review concluded that benperidol was as effective as other antipsychotics, with a similar side effect profile.

In summary, benperidol is mainly used for treating schizophrenia and other psychotic disorders. Clinical studies have demonstrated its effectiveness in managing psychotic symptoms, with comparable efficacy to other antipsychotic medications.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

  • The British National Formulary (BNF)
  • Electronic medicines compendium (emc)
  • The National Library of Medicine's DailyMed
  • The Food and Drug Administration (FDA) 
  • Different drug forms like tablets or liquids have specific patient information leaflets (PIL) for various doses. Refer to the PIL for your prescribed drug form and dose.

    Search for PILs on websites like:

    France

    • ANSM (Agence nationale de sécurité du médicament et des produits de santé): ansm.sante.fr

    Spain

    • AEMPS (Agencia Española de Medicamentos y Productos Sanitarios): aemps.gob.es

    Germany

    • BfArM (Bundesinstitut für Arzneimittel und Medizinprodukte): bfarm.de

    Italy

    For questions about your medication:

    • Consult your doctor, a healthcare professional, or a pharmacist

    France

    • Contact SOS Médecins: 3624
    • For mental health support, contact SOS Suicide: 01 45 39 40 00

    Belgium (French)

    Switzerland (French)

    • La Main Tendue: 143
    • Website: 143.ch

    Canada (French)

    • Centre de prévention du suicide du Québec: 1 866 APPELLE (1 866 277-3553)
    • Website: cpsquebec.ca

    Spain

    • Contact emergency number: 112
    • For mental health support, contact Teléfono de la Esperanza: 717 003 717

    Germany

    • Contact emergency number: 112
    • For mental health support, contact Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222

    Italy

    • Contact emergency number: 112
    • For mental health support, contact Telefono Amico: 199 284 284

    Netherlands

    • Contact emergency number: 112
    • For mental health support, contact 113 Zelfmoordpreventie: 0800 0113

    Portugal

    • Contact emergency number: 112
    • For mental health support, contact Sos Voz Amiga: 21 354 45 45, 91 280 26 69, or 96 352 46 60

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