Why is nortriptyline taken at night?

Nortriptyline is often taken at night because it can cause drowsiness and sedation, which may interfere with daily activities if taken during the day. Taking nortriptyline at night can help individuals with depression, anxiety, or chronic pain to fall asleep more easily and stay asleep longer, while also reducing the risk of daytime drowsiness.

In addition, taking nortriptyline at night may help to enhance its effectiveness in treating certain conditions, such as depression or anxiety. This is because the body’s natural circadian rhythm, or sleep-wake cycle, affects the way that medications are absorbed, metabolized, and distributed throughout the body. Some medications, including nortriptyline, may be more effective when taken at specific times of the day or night, based on their pharmacokinetic and pharmacodynamic properties.

It is important to follow all instructions for taking nortriptyline and to take it on a regular schedule, as directed by a healthcare provider. If you have any concerns about the timing or dosing of nortriptyline, it is important to discuss these with a healthcare provider, who can help determine the most appropriate treatment plan based on individual needs and medical history.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: