Citalopram is a medication that is primarily used to treat depression and anxiety disorders, such as generalized anxiety disorder and panic disorder. Citalopram is a selective serotonin reuptake inhibitor (SSRI), which means that it works by increasing the levels of serotonin in the brain.
Depression:
2.A meta-analysis of 117 randomized controlled trials found that SSRIs, including citalopram, were effective in treating depression. The study found that SSRIs were more effective than placebo in reducing symptoms of depression, and that they had a favorable safety profile compared to other antidepressant medications.
Anxiety Disorders:
Several studies have found that citalopram is effective in treating anxiety disorders, such as generalized anxiety disorder and panic disorder. A review of 14 randomized controlled trials found that SSRIs, including citalopram, were effective in treating generalized anxiety disorder, and that they had a favorable safety profile compared to other medications.
Overall, citalopram is an effective medication for the treatment of depression and anxiety disorders. However, like all medications, citalopram can cause side effects, and it is important to take the medication only as prescribed by a healthcare professional.
Sources:
- Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., … & Geddes, J. R. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. PLOS ONE, 13(5), e0196975.
- Bandelow, B., Reitt, M., Röver, C., Michaelis, S., Görlich, Y., & Wedekind, D. (2015). Efficacy of treatments for anxiety disorders: a meta-analysis. International Clinical Psychopharmacology, 30(4), 183–192.
- Baldwin, D. S., Anderson, I. M., Nutt, D. J., Allgulander, C., Bandelow, B., den Boer, J. A., … & Wittchen, H. U. (2005). Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology, 19(6), 567–596.
Related Questions (FAQ)
How Does Bupropion XL Make You Feel?
Bupropion XL often helps people feel more motivated, energetic, and emotionally balanced without the emotional numbness seen with some SSRIs. During the first weeks, mild anxiety, insomnia, or restlessness may appear before mood and focus noticeably improve. Most users report feeling “lighter” and more alert once their body adjusts.
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Wellbutrin SR vs XL: Which Is Better for You?
Bottom line: SR and XL work about the same for depression; XL’s once-daily, smoother release often fits busy routines and may reduce peak-related side effects (jitters, nausea, headache).
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Is 300 mg of Bupropion XL Considered a High Dose?
A 300 mg daily dose of Bupropion XL is generally considered a standard therapeutic amount — not unusually high, but on the upper end of the typical range (150 mg – 450 mg/day). For most patients, it balances strong antidepressant effects with manageable side-effect risk, though it should always be monitored by a doctor.
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Why take Lexapro and Wellbutrin together?
Doctors may prescribe Lexapro (escitalopram) and Wellbutrin (bupropion) together to treat depression or anxiety more effectively. Lexapro increases serotonin levels, improving mood and calmness, while Wellbutrin boosts dopamine and norepinephrine, enhancing energy and motivation. The combination can balance emotional stability and focus while reducing sexual side effects or fatigue from SSRI therapy.
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Can you take Wellbutrin and an Antipsychotic?
Yes, Wellbutrin (bupropion) can sometimes be taken with an antipsychotic under close medical supervision. This combination may help manage both depressive and psychotic symptoms by balancing dopamine, norepinephrine, and serotonin activity. However, it increases the risk of seizures and interactions, so dosage and monitoring must be tailored by a psychiatrist.
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Is Vraylar better than Wellbutrin?
Vraylar (cariprazine) and Wellbutrin (bupropion) serve different roles—Vraylar treats bipolar disorder and schizophrenia, while Wellbutrin addresses depression and low motivation. One isn’t “better” than the other; the right choice depends on the condition being treated, side-effect tolerance, and individual response under a doctor’s supervision.
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