Who should not take bupropion?

Bupropion is an antidepressant medication that can be effective for treating depression, smoking cessation, and other conditions. However, there are certain individuals who should not take bupropion or who should use caution when taking the medication. Here are some groups of people who should not take bupropion:

1. Individuals with a history of seizures:
   Bupropion may lower the seizure threshold and increase the risk of seizures, particularly in individuals who have a history of seizures or other conditions that may increase the risk of seizures. Therefore, bupropion is contraindicated in individuals with a seizure disorder or a history of seizures.
2. Individuals with an eating disorder:
   Bupropion may increase the risk of seizures, particularly in individuals with an eating disorder such as bulimia or anorexia nervosa. Therefore, bupropion is contraindicated in individuals with a current or prior diagnosis of an eating disorder.
3. Individuals who are allergic to bupropion or any of its components:
   Bupropion may cause an allergic reaction in some individuals, particularly those who are allergic to bupropion or any of its components. Therefore, bupropion should not be taken by individuals who are allergic to the medication.
4. Individuals taking certain medications:
   Bupropion may interact with certain medications, such as monoamine oxidase inhibitors (MAOIs), and may increase the risk of serious side effects such as seizures, high blood pressure, and serotonin syndrome. Therefore, bupropion should not be taken by individuals taking MAOIs or other medications that interact with bupropion.
5. Individuals with a history of bipolar disorder:
   Bupropion may increase the risk of mania or hypomania, particularly in individuals with a history of bipolar disorder. Therefore, bupropion should be used with caution in individuals with a history of bipolar disorder or other mood disorders.

It is important to only take bupropion as prescribed by a healthcare provider and to follow their instructions carefully. If you have any questions or concerns about your medication regimen, it is important to discuss these with your healthcare provider.