Why does aripiprazole make me feel high?

Aripiprazole is not typically associated with causing a “high” or euphoric feeling. However, some individuals may experience a range of sensations or changes in mood while taking the medication, and these may be perceived as feeling high.

The exact reason why some individuals may experience these sensations while taking aripiprazole is not fully understood, but it may be related to changes in the activity of neurotransmitters in the brain or changes in mood. Aripiprazole can modulate the activity of dopamine, which is a neurotransmitter that is involved in pleasure, reward, and motivation. By affecting dopamine activity, aripiprazole can alter the way individuals experience pleasure or reward, which may be perceived as feeling high.

It is important to note that some individuals may be more susceptible to these effects than others, and the experience of feeling high while taking aripiprazole is not common. If an individual experiences concerning changes in mood or sensations while taking aripiprazole, they should speak with their healthcare provider. The healthcare provider may adjust the dosage or consider switching to a different medication to help manage side effects.

There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: