Is agomelatine a stimulant?

No, agomelatine is not a stimulant. Agomelatine is an antidepressant medication that works by modulating the activity of both melatonin and serotonin receptors in the brain. Its mechanism of action is different from that of stimulant medications, which work by increasing the activity of certain neurotransmitters in the brain, such as dopamine and norepinephrine.

In fact, agomelatine is known for its sedative effects and may cause drowsiness or fatigue in some individuals. It is typically taken in the evening, shortly before bedtime, to help regulate sleep-wake cycles and improve sleep quality.

It is important to note that not all individuals with depression or anxiety will respond to agomelatine, and it may not be the best choice of medication for everyone. The decision to use agomelatine or any other medication should be made in consultation with a healthcare provider, who can help determine the most appropriate treatment plan based on individual needs and medical history.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as: