What hormones does bupropion affect?

Bupropion primarily affects the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine. However, it may also have some effects on other hormones and neurotransmitters in the body.

For example, bupropion has been shown to increase levels of the hormone prolactin, which is involved in lactation, reproduction, and mood regulation.

Bupropion may also affect cortisol levels, which is a stress hormone that is involved in regulating energy metabolism, immune function, and other physiological processes.

Additionally, bupropion may have some effects on serotonin levels, which is a neurotransmitter that is involved in regulating mood, appetite, sleep, and other functions.

Overall, bupropion’s effects on hormones and neurotransmitters in the body can help regulate mood, energy, motivation, and other brain and body functions. It is important to only take bupropion as prescribed by a healthcare provider and to follow their instructions carefully.


There are various forms of drugs available, such as tablets or liquids, and each may have a separate patient information leaflet (PIL) for different doses. It is important to refer to the PIL for the specific form and dose of the drug that you have been prescribed.

You can search for further information and PILs on websites such as:

Does bupropion increase GABA?

What happens when you stop taking bupropion?